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When combined with NAD+, a dual sirtuin stimulation arises, more substrate (NAD+) + direct activator (resveratrol)

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This release of histamine is what typically triggers allergy symptoms such as sneezing, itching, and inflammation

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Polypeptide adolapin suppresses prostaglandin production and inhibits the action of PLA2 and human lipoxygenase (Tusiimire et al., 2016)