Comparison of the Effects of L-Carnitine and Acetyl-L-Carnitine on Carnitine Levels, Ambulatory Activity, and Oxidative Stress Biomarkers in the Brain of Old Rats
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Una cantidad suficiente de carnitina libre permite que el acil-CoA acumulado entre en las mitocondrias, reduce su inhibicin sobre la adenina nucletido translocasa y permite que la fosforilacin oxidativa proceda sin problemas
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However, a substantial inhibition of OCTN2-mediated uptake of colistin in the presence of L-carnitine is unlikely at the concentrations used in our experiments due to the nature of their binding within the OCTN2 pocket 15
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