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The efficacy of treatments of comorbid pain and depression has been less studied, but it is well known that these two conditions worsen each others severity and therapeutic response

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Peripheral neuropathy is also a leading cause of lower limb amputation in diabetic patients (68)

We modelled four interventions: increase in use of SGLT2is or GLP-1 RAs to 75% of the total population with type 2 diabetes, and increase in use of SGLT2is or GLP-1 RAs to 75% of the secondary prevention population (i.e

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