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Cochrane Database Syst Rev 12(12):CD011901

But recently, GLP-1s have gained mainstream attention and adoption due to their applications for weight lossoriginally highlighted as a side effect. Those findings led to widespread media coverage and celebrity endorsements, helping fuel a rapid increase in interest and prescribing of GLP-1 medications

But it took roughly 60 times the subcutaneous dose to get equivalent blood sugar effects, and the cost of that much insulin made the product commercially impractical

An activating mutation in the kinase homology domain of the natriuretic peptide receptor-2 causes extremely tall stature without skeletal deformities

Mukherjee S, Skrede S, Haugstyl M, Lpez M, Fern J