Antioxidant Enzymes in Endometriosis Sep 7, 2020 Association between Genetic Variants of Antioxidant Enzymes and Severity of Endometriosis Key Points Highlight: Glutathione peroxidase 4 (GPX4), an enzyme that protects cells against oxidative stress, might contribute to the pathogenesis of endometriosis
This effect is mediated by SIRT1/p66Shc pathway (Sampaio et al., 2016)
Albumin and alpha-lactalbumin help with the transport and absorption of other nutrients
Eat a Healthy Diet Consuming a balanced diet containing antioxidant properties will help the body naturally produce glutathione
Gene set enrichment analysis showed upregulation of MYC and p53 targets after 24 hours of oxidative damage, as well as upregulation of pathways related to cell cycle control, DNA repair, and telomere maintenance, and downregulation of glycolysis, T cell receptor complexes, and other metabolic processes
Histamine Overload and MCAS Flares: As a key component of Phase II liver detoxification, glutathione accelerates the clearance of circulating histamine and inflammatory cytokines, helping to reduce flushing, itching, and sudden allergic-like reactions