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The mice were then intraperitoneally injected with either AP probe-net (0.025 or 0.05 mg/kg/d with a volume of 500 l every two days) or dimethyl sulfoxide (DMSO) for the negative control

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This pattern mirrors whats seen in other chronic conditions, where relapses occur once treatment stops

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Subsequently, within endosomes, plasmacytoid dendritic cells (pDCs) recognize the released RNA ligands via TLR7, initiating the TLR7MyD88 signaling cascade