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Natural disease course of ulcerative colitis during the first five years of follow-up in a European population-based inception cohort-an Epi-IBD study

NNMT catalyses the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, the precursor in the NAD+ salvage pathway

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4 Unfortunately, both forms can still cause unwanted side effects

Withdrawal rates due to adverse effects serve as a practical measure of real-world tolerability, as they reflect whether side effects are bothersome enough to outweigh potential benefits

Available evidence suggests AHK-Cu is well tolerated with topical application