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Mechanistic investigations often pair 5-Amino-1MQ treatment with transcriptomic and proteomic analyses to map the downstream signaling changes that accompany NNMT inhibition, establishing a fuller picture of the enzyme's regulatory network

Sangle, Prerna, et al

The route prescribed

Treat the underlying inflammation

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The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system. The Journal of Pharmacology and Experimental Therapeutics vol