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Specifically, the higher dose was associated with a 45% lower decline in ALSFRS-R scores and a delay in the need for full ventilation support or death by nearly two years compared with a placebo

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Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinsons disease

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Exercise induces brown adipose tissue to secrete neuregulin 4 (Nrg4), which inhibits cGAS activity via ErbB4/AKT phosphorylation, blocking inflammatory and steatotic signals

In comparison, over the same time span, placebo comparators lost 2.2% BMI