It was shown to induce the proliferation of PCa cells, both directly through CCR6-mediated proliferation and indirectly through enhanced recruitment of inflammatory cells such as Th17 [398]
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Since host and viral targets of ubiquitination and ISGylation are often directed to degradation, components of the proteasome, proteases, protein folding factors, and chaperones are 1.51.8-fold upregulated
While it is crucial to reiterate that this combination has not been studied in formal clinical trials and remains an off-label experimental approach primarily discussed within biohacking and peptide research communities, the scientific rationale is intriguing
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