Issue 1: a thin clinical-trial evidence base relative to the marketing The public GHK-Cu literature spans more than 250 papers, the majority of which are in-vitro (cell-culture) or small animal model work
Studies demonstrate the peptide reduces neuronal death in cell culture models of oxidative stress and glutamate excitotoxicity, with protective effects observed at the same ultralow concentrations that produce cognitive enhancement

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You may also notice that you urinate a bit more after a lipotropic injection