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Moreover, the optimal dosing strategy for this combination has not been established

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Serious side effects may include pancreatitis, gallstones, low blood sugar (hypoglycemia), kidney problems including kidney failure, changes in vision in people with type 2 diabetes, increased resting heart rate, depression or thoughts of suicide

Resuming after prolonged interruption may require restarting at a lower dose to re-establish tolerance and minimise gastrointestinal side effects

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