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They mimic the action of endogenous GLP-1, a hormone naturally released by cells in the small intestine in response to food intake and exert effects 16 (Figure 1) in a dose-dependent manner 17

The primary endpoints was the percent change from baseline in body weight, while secondary endpoints included change from baseline in body mass index (BMI), waist circumference and systolic blood pressure

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From quick and easy GLP-1 breakfasts to satisfying dinners for GLP-1 diets, youll find meal ideas that fit your taste preferences, appetite level, and nutrition needs

doi:10.1038/nutd.2011.24

The biology, in short, is where the next generation of these drugs will be designed