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The variance was filtered by default optimisation settings and a predefined standard deviation of p = 0.005 comparing untreated HepG2 and HepG2 ATP7B-KO resulted in an FDR of q = 0.01788

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10.4 Ocular delivery barriers and potential side effects The bloodretinal barrier, composed of tight junctions in retinal vascular endothelial cells and the RPE, hinders the penetration of macromolecular drugs (such as iron chelators) into the posterior segment of the eye (181)

Example: 10 mg 2 mL = 5 mg/mL Example: 5 mg 1 mL = 5 mg/mL (same concentration, half the volume) The syringe-unit bridge: Insulin syringes are marked in "units", not millilitres

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Fully recyclable packaging and supporting environmental regeneration