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Cytoprotective, antioxidant, and antitumor effects in preclinical models, including reduced lipid peroxidation products, lower reactive oxygen species (ROS) levels, and suppression of certain chemically induced tumors

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M., & Arslan, E

Heparanase is also overexpressed in some malignant tumors and is activated in sepsis, causing partial degradation of the glycocalyx, which further exacerbates the loss of glycocalyx components (65)