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Marissa Kinney and Lola Holcomb were supported by US National Science Foundation One Health and the Environment (OH&E): Convergence of Social and Biological Sciences NRT program grant DGE-1922560, and Lola Holcomb was supported by the UMaine Graduate School of Biomedical Science and Engineering

Ipamorelin is a synthetic pentapeptide that functions as a selective agonist of the growth hormone secretagogue receptor (GHSR)

Cyclodextrins are well explored in ocular drug delivery and are generally regarded as safe, as they do not permeate through the biological membrane and only act as a carrier to increase drug availability for enhanced permeation [90, 91]

Dysfunctional hypothalamic function can be seen in ME/CFS patients in the form of up-regulation of hypothalamic 5-hydroxytryptamine (5-HT) receptors (441) and abnormal arginine/vasopressin responses to deprivation tests and water loading (440)

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