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Methods Ethics statement This study was approved by the Conjoint Health Research Ethics Board (CHREB), University of Calgary (REB23-0538)

J Biol Chem 276: 30983105

Baseline BRET measurements were taken for 2 min before the addition of the vehicle or ligand

Rotating between sites prevents injection site reactions and ensures consistent absorption

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Ruff CT, Baron M, Im K, ODonoghue ML, Fiedorek FT, Sabatine MS (2022) Subcutaneous infusion of exenatide and cardiovascular outcomes in type 2 diabetes: a non-inferiority randomized controlled trial