Conclusions This study highlights substantial demand for GLP-1 and GLP-1/GIP medications to support weight loss in Great Britain
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American Association of Clinical Endocrinology (AACE)
Losing weight can be challenging
By engaging both GIP and GLP-1 pathways, it allows researchers to study how coordinated receptor activation influences downstream biological responses
Higher Risks of Gastrointestinal Effects in Diabetic Patients In October 2023, The Journal of the American Medical Association(JAMA), examined adverse events in patients with diabetes associated with GLP-1 RA in a research letter called Risk of Gastrointestinal Adverse Events Associated With Glucagon-Like Peptide-1 Receptor Agonists for Weight Loss where it concluded that studies have found increased risks of gastrointestinal adverse events, such as biliary disease, pancreatitis, bowel obstruction, and gastroparesis