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Initiation of saxagliptin and metformin hydrochloride extended-release tablets is not recommended in patients with eGFR between 30 and 45 mL/minute/1.73 m2

If a patient cannot maintain hydration for more than 24 hours, our escalation pathway requires an immediate suspension of treatment and a clinical review to protect the biological health of the kidneys

After opening, compounded semaglutide can remain refrigerated for a defined periodtypically 28 daysdepending on your specific compounding pharmacy's stability data

There is no way to rescue it

PMID: 29866886

Refrigeration helps prevent degradation of the peptide structure of semaglutide and maintains the stability of cyanocobalamin, which can be sensitive to heat and light exposure