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Deeper understanding of these mechanisms may revolutionize the therapeutics of obesity, diabetes, and related disorders through interventions that harmonize sensory experience with metabolic needs

However, HGHs direct lipolytic effects often improve insulin sensitivity through fat loss, potentially offsetting any direct insulin-antagonistic effects of elevated IGF-1

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By increasing GLP-1 production or stimulating its release, this approach can complement existing therapies, such as GLP-1RAs and DPP-4 inhibitors, offering additional benefits while potentially reducing side effects

Retrieved from Borrelli, F., Colalto, C., Delfino, D