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When incorporated into proteins, histidines side chain can act as a proton acceptor and donor, conveying important properties when combined into enzymes such as chymotrypsin and those involved in the metabolism of carbohydrates, proteins, and nucleic acids
During in vitro fertilization, this supplementation may reduce the demand for gonadotropins, thereby improving the response to follicle pre-stimulation (Gat et al., 2016)
[PubMed] Jett, Lucie, Leger, Roger, Thibaudeau, Karen, Benquet, Corinne, Robitaille, Martin, Pellerin, Isabelle, Paradis, Vronique, Wyk, Pieter, Pham, Khan, Bridon, Dominique
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Numerous studies have demonstrated that HO-1 has a significant effect on diabetic complications, with induction of HO-1 protein expression enhancing antioxidant defense and reducing inflammatory factors (Table 2)