Weight Loss and Hormonal Shifts : Rapid weight loss can impact hormone levels, including cortisol, which may contribute to restless nights
If eating enough feels difficult because of nausea, anxiety, body-image pressure, or medication side effects, tell your provider

Abbreviations WHO: World Health Organization TAK1: Transforming growth factor- -activated kinase 1 MO: Moringa oleifera AGE: Advanced Glycation Endproducts MyD88: Myeloid differentiation primary response protein TNF- : Tumor Necrosis Factor- IKKB: Inhibitory kB kinase beta RAGE: Advanced glycation endproduct receptor NQO1: NAD(P)H quinone dehydrogenase ROS: Reactive oxygen species CAT: Catalase HO-1: Heme oxygenase-1 SOD: Sodium dismutase NOX: NADPH-oxidase IKK: Inhibitory KB kinase alpha TRAF6: TNF receptor-associated factor 6 Keap1: Kelch-like ECH associated protein 1 LPS: Lipopolysaccharides MCP-1: Monocyte chemoattractant protein Nrt2: Nuclear factor erythroid 2-related factor 2 TLR4: Toll-like receptor 4 NFB: Nuclear factor kappa-light-chain-enhancer of activated B cells Nrf2: Nuclear factor erythroid 2-related factor 2 Keap: Kelch-like ECH-associated protein 1 ARE: Antioxidant response element
The formulation difference matters less than most patients expect
Digestion 56:493501 Lee A, Patrick P, Wishart J, Horowitz M, Morley JE (2002) The effects of miglitol on glucagon-like peptide-1 secretion and appetite sensations in obese type 2 diabetics
Our guide to getting off GLP-1 covers the full discontinuation framework