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Microsomes (1 mg/ml) in sodium phosphate buffer, pH 7.4 were supplemented with NADPH (10 mM) and NFT (5 mM)
ACS Omega 2 , 24992506, (2017)
10.1038/224117a0 Nature
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The porcine pi-class enzyme pGTSP1-1 was the first GST to have its structure determined, and it is representative of other members of the cytosolic GST superfamily, which contain a thioredoxin-like N -terminal domain as well as a C -terminal domain consisting of alpha helices
This is likely due to glutathione's role in cellular energy production and its ability to reduce cellular stress
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