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3 Vitamin D mechanisms of action as a modulator of neuroplasticity and cognitive function in aging and neurodegenerative conditions Vitamin D, traditionally recognized for its role in calcium homeostasis and bone metabolism, is now increasingly understood to function as a neurosteroid (56, 57)

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Fluoxetine administration to treat depression during pregnancy has been shown to induce greater changes in gene expression in the placenta of male infants than in that of female infants, emphasizing its sex-specific effects (Staal et al., 2024)