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Half of the participants who did not respond to one drug, did respond to the other drug or their combination, as highlighted by the colored hatched bars (Fig

Gastrointestinal complaints were most common, including [1, 12]: Indigestion Constipation Nausea Diarrhea Abdominal pain Vomiting These outcomes were dependent on dosage and timing, likely caused by alterations in gastric motility and intestinal uptake