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Thus, administration of exogenous GSH exerts a therapeutic effect on ischemic stroke by increasing intrastriatal DA, and the accumulated DA can, in turn, enhance the exposure of GSH and its related substances, thus promoting the therapeutic effect of GSH

The majority of these gut hormones are anorexigenic and include peptide tyrosine- tyrosine (PYY), pancreatic polypeptide (PP), glucagon-like peptide-1(GLP-1), oxyntomodulin (OXM) and cholecystokinin (CCK)

Common side effects, rare but serious risks, high costs, and the need for long-term use all deserve careful thought

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Ann Intern Med, 114: 678-693