Agbai, MD, a dermatologist at UC Davis Health in Sacramento, California, who specializes in multicultural dermatology
Multi-systemic effects Beyond sleep, DSIP influences thermoregulation, heart rate, blood pressure, pain threshold, and immune function
human research : Most research has been conducted in rodents and small mammals, so it is not yet clear how these findings may translate to humans
One study found people with obesity who had higher levels of glutathione lost more weight when they followed a healthy eating plan for 6 months
Mathematical Framework for Human Equivalent Dose The human equivalent dose (HED) formula is: HED (mg/kg) = Animal dose (mg/kg) (Animal Km / Human Km) Standard Km constants used in pharmacological scaling are: Rat Km = 6 Human Km = 37 To illustrate: If a rat study administers 10 mcg/kg, convert micrograms to milligrams: 10 mcg = 0.01 mg HED = 0.01 (6 / 37) HED 0.00162 mg/kg HED 1.62 mcg/kg For a 70 kg individual: 70 1.62 mcg 113 mcg This represents a mathematically scaled equivalent exposurenot a prescription
The body relies on amino acids, vitamins, and minerals to support its natural glutathione production