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Its because we have these tools weve built up at MIT over the years. They also synthesized a shorter sequence of only 12 amino acids found in the alpha helix, and then tested both of the peptides using equipment at MITs Biophysical Instrumentation Facility that can measure how strongly two molecules bind together

In simulation box, periodic boundary conditions were applied and ER protein or ER -DNA complexes centered in a cubic box (minimum 1.0 nm edge distance) with TIP3P water as solvent