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However, little experimental work has been done regarding lens changes in response to variations in levels of this nutrient

Knudsen LB, Nielsen PF, Huusfeldt PO, Johansen NL, Madsen K, Pedersen FZ, Thgersen H, Wilken M, Agers H

Given the increasing interest in peptide drugs because of their low production costs, high potency, selectivity, and biological stability, our research underscores the potential of finding a peptide analgesic that precisely targets and modulates TRPV1 without causing adverse effects

Mechanism of Action L-Carnitine transfers long chain FAs into the mitochondria Required for Energy Production Evidence of Benefits Orer & Guzel Double-blind study examined L-Carnitinesupplementation on endurance performance of professional soccer players 2 groups: 1 received 3g L-Carnitine, 1 received 4g Exercise test: Running at 10km/hr, increasing 1 km/hr every 3 minutes Heart rate, Lactic Acid concentrations, & perceived level of difficulty were measured The test was performed using a placebo, 1 week later Results of the study L-carnitine supplementation increased the effectiveness of endurance performance Heart rate decreased Lactic Acid Concentrations decreased Running speeds increased Exhaustion was prolonged (perceived level of difficulty) Conflicting Research Colombani et al Double-blind study examined the effect of L-Carnitine supplementation on the performance of marathon runners Results No significant change in marathon running time L-Carnitine did not improve physical performance Safety Concerns No serious toxicity has been reported With doses over 6000mg: Nausea Vomiting Diarrhea Professional Position L-carnitine is proven to be effective in the treatment of many diseases, & generally safe and non-toxic if taken in doses less than 6g Though there seems to be inconsistent evidence in its effectiveness of exercise performance, there is a greater possibility of benefits References Colombani, P

It enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways

Its anti-inflammatory effects also help calm chronic skin irritation that contributes to wrinkle formation