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In Doctor Koshiba's expert opinion, the alternative on offer - high-dose oral B12 (typically 1000-2000 mcg daily) - can be quite effective for many people

The gut microbiome was altered upon intragastric administration of DADS of rat, a low dose of DADS decreased Bacteroidetes phyla but increased Firmicutes phyla bacteria (Yang et al., 2019)

Bianchi GP, Marchesini G, Fabbri A, et al

Get a comprehensive hormone panel If you have not had your sex hormones checked since starting GLP-1 therapy, request a full panel including total and free testosterone, estradiol, SHBG, LH, FSH, and thyroid function

Most candidates fall into two broad categories: BMI 30 kg/m or BMI 27 kg/m with weight-related comorbidities like hypertension or type 2 diabetes

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