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As multi-agonists secure approvals, reimbursement authorities may reward stronger risk-reduction profiles, underpinning sustained GLP-1 diabetes drugs market expansion in the latter half of the decade

It may be mixed with a substance known as a buffering agent or excipient to maintain its stability, purity, and the correct pH for storage and administration

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The first two reports, both 4 week studies in drug nave patients with relatively mild T2DM, showed that DPP-4 inhibition was well-tolerated in humans and was associated with significantly lower fasting and meal-related glucose concentrations (32, 33)

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Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, Zavarzina NY, Semenchenko AV, Yashin AI