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In published pre-clinical studies, both peptides are most commonly administered via subcutaneous (SubQ) or intramuscular (IM) injection

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Sustained weight loss with combined LEAP2 and semaglutide treatment in mice

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Dosing tiers: Topical application (creams containing 1-3% GHK-Cu) targets skin-specific aging: wrinkles, laxity, and hyperpigmentation

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Small cystic areas were noted

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