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Altintas also noted that if these findings are confirmed by prospective studies, several important clinical implications emerge. First, clinicians may be less concerned that semaglutide-induced weight loss inherently increases fracture risk in patients with type 2 diabetes

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Despite the extensive fundamental basis for the use of GLP-1RAs in AD, formed as a result of preclinical and a number of clinical studies, the analysis of the clinical results of the use of GLP-1RAs does not always reveal reliable effects on the cognitive sphere

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The Leyden 2002 facial-cream trial reported skin density, thickness, fine lines, and laxity changes at 12 weeks