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However, high-dose vitamin C can cause significant local tissue irritation if it leaks outside the vein, so the distinction still matters

GHK-Cu's Unique Regulatory Situation What makes GHK-Cu's regulatory story unique is its dual classification based on route of administration: What This Means Non-injectable GHK-Cu (topical creams, serums, etc.) was in Category 1 meaning it was under evaluation but generally available for compounding

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Besides, cell penetrating peptides seem promising to increase skin permeation of GHK and its derivatives

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