PGC-1 upregulates the expression of GLUT4 in skeletal muscle [103,104,105], inhibits pro-inflammatory cytokine production [106], and is a co-activator of the retinoic X receptor (RXR) [83,85,107]
Best Supplements to Take While on GLP-1s at a Glance Best Overall: Happy Mammoth Prebiotic Collagen Protein, $70 Best Runner Up: Pure Encapsulations Magnesium (Glycinate), $27 Best Omega-3 Fish Oil: Nordic Naturals Omega-3, $20 Best Hybrid Supplement: Pure Encapsulations Vitamin D3 & K2, $19 Best Vitamin B12: Thorne Vitamin B12, $24 Best Digestive Enzymes: Happy V Debloat + Digest, $40 (30-day supply) Best Vitamin D: Pure Encapsulations Vitamin D3 Liquid, $33 Best Fiber: Sakara Fiber Super Powder, $45 Best Electrolytes: Waterboy Daily Hydration, $40 (was $50) Best Protein Powder: Promix Whey Protein Powder, $64 Best Multivitamin: Olly Womens Multi, $16 Do You Need Supplements While on a GLP-1
Therapy aims to enhance these processes by increasing NAD+ levels
Some evidence for modest reduction in post-exercise muscle damage biomarkers
For those on GLP-1 medications like Semaglutide and Tirzepatide for weight loss, theres an additional layer of consideration: whether to continue taking these medications during the trip or to pause until you return
doi: 10.1038/cddis.2016.208 53 XuQKanthasamyAGJinHReddyMB
