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Those who may not be a good candidate for GLP-1 medication use severe gastrointestinal diseases (e.g., inflammatory bowel disease) a personal or family history of multiple endocrine neoplasia 2A or 2B a personal or family history of medullary thyroid cancer a history of pancreatitis If youre in perimenopause, pregnancy is still possible, and doctors advise against using semaglutide during pregnancy

Still, its efficacy case remains unproven at the scale Tesamorelin has demonstrated.

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There is no clinical data on combining GLP-1 Complete with pharmaceutical GLP-1 receptor agonists

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However, they can be expensive, are in limited supply, and come with unpleasant side effects