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While these incretin-based therapies improve glycemic control and promote weight loss, they also influence appetite, gastric emptying, and substrate utilization

Given that the IC 100 concentration of niclosamide required to completely prevent viral replication in SARS-CoV-2 infected Calu-3 lung cells as measured by Ko et al (34) as 2M, a 20uM niclosamide solution nasal spray is 10x this IC 100

Their mechanisms complement each other: The combination does not cause hypoglycaemia (neither drug by itself causes low blood sugar in most patients), making it generally safe from a glucose management perspective

How Boost Synergy GLP-1 Supports GLP-1 Secretion GLP-1 is critical in managing appetite, insulin secretion, and weight control

Most side effects diminish within weeks as the body adapts