More recently, encouraging clinical results from a triple-hormone-receptor agonist, Retatrutide, and several GLP-1R/GCGR dual agonists, suggest that GCGR could be a promising co-stimulating target for type 2 diabetes and obesity
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Specifically, we included the SN, STN, thalamus, GPi, GPe and striatum as delineated in the HybraPD atlas 112
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Patients included in the retrospective cohort analysis were over 18 years old, had a confirmed diagnosis of psoriasis requiring systemic therapy, and had received continuous treatment with either a GLP-1 RA or an alternative anti-diabetic or anti-obesity medication for at least 24 months
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