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Iborra FJ, Kimura H, Cook PR

Our plan is for you to lose your unwanted weight while combining the medication with other lifestyle interventions, such as diet and exercise

10.1038/s41419-019-1734-7 258 YangQ.ZhaoQ.YinY

Limitations of Weight Loss Medications: Modest weight loss: Compared to bariatric surgery, weight loss with medications tends to be more modest, typically in the range of 5-15% of body weight

This is a critical methodological confounder that has been inflating the perceived muscle wasting signal in large clinical trials

The authors have given talks and attended conferences sponsored by various pharmaceutical companies, including Bristol-Myers Squibb, Pfizer, Lilly, Abbott, Amgen, Astrazeneca, Novartis, Vianex, Teva, and MSD