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Because GLP-1 therapy works through appetite and fullness signaling, understanding how GLP-1 medications support weight loss can make the comparison between semaglutide and tirzepatide easier to understand

3 For body weight the change from baseline and difference to placebo the unit is percentage change from baseline

Alger, H.M

While some patients choose to stay on Semaglutide long-term, others may be able to maintain their weight loss through lifestyle changes once their goal weight is reached

Despite these differences, both drugs are semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist

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