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Male SpragueDawley (SD) rats weighing 200 20 g were obtained from the Animal Experiment Center of the Fourth Military Medical University (Xian, China) and housed in a specific pathogen-free animal facility

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These animals were also subjected to the same environmental conditions and treatment protocols for a chronic 28-day administration study [2]

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Deficiency is common and may be associated with fatigue, cognitive changes, mood disturbance, and peripheral neuropathy