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[3] This matters enormously for interpretation: a result obtained with CagriSema describes cagrilintide plus a potent GLP-1 analog, and cannot be read as the effect of cagrilintide by itself

When sepsis develops, inflammatory stimuli cause the degradation of high-molecular weight HA to the low-molecular weight form, and the accumulation of this form triggers an inflammatory response with the aim of eliminating pathogens (70)

(64(2)):217-219 doi:10.1016/j.jemermed.2022.10.024