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Certain enteric pathogens possess mechanisms that enable their direct adherence to IECS while others permit the secretion of effector proteins or enterotoxins via membrane localised secretion systems that typically target TJs thereby increasing intestinal permeability by disrupting the intracellular cytoskeleton of IECs (Knig et al

de la Chapelle, et al

Transforming growth factor beta (TGF-): Promotes chondrocyte proliferation and matrix synthesis

Dalton, T

Arginine is the primary substrate for nitric oxide synthase, the enzyme that produces nitric oxide in the body

The D-CuP is synthesized and then incorporated into a reactive oxygen species (ROS)-responsive hydrogel matrix to improve therapeutic compliance, culminating in the formulation of G/D-CuP