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Aging and Longevity Research Age-related changes in L-Carnitine metabolism and mitochondrial function connect to fundamental aging research: Mitochondrial Aging Research: Investigation of age-related mitochondrial dysfunction, decreased oxidative capacity, increased ROS production, and altered mitochondrial dynamics

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It creates confounding variables that are impossible to trace unless you suspect storage was the issue

The AGES-Reykjavik Study suggests that change in kidney measures is associated with subclinical brain pathology in older community-dwelling persons