tirzepatide 2.0 Dosage for Weight Loss Eli Lilly Launches Self-Pay Vials

While we employed Steiger filtering to test the direction of causation as a sensitivity analysis, we note that its statistical power can be suboptimal when binary outcomes are involved

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Moreover, despite statistical significance, the improvements did not reach minimal clinically important difference (MCID) thresholds for all patients (Ghorbani et al., 2024)

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Currently (February 2024), the EMA is considering the wider use of Wegovy to include reducing cardiovascular events this is critical for coverage in many European health systems, including the largest, Germany, which refuse to cover it for weight loss alone