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That assumption is where contamination, concentration errors, and peptide degradation begin

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Venlafaxine showed the highest risk estimate among antidepressants, though no statistically significant relative risk (RR) (4.53 (95% CI 0.4743.25)), and was the only compound with consistent signals of increased switch in individual studies

The anti-amyloid antibodies of the 2020s, the first drugs ever to bend the course of the disease at all, did it the hard way: enormous multi-country trials with pre-specified cognitive endpoints, full publication in the New England Journal of Medicine and JAMA , and a brutal public fight over whether their modest benefit was even worth the brain-swelling risk