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Twenty four hours after transfection, cells were washed 1 with PBS and imaged by time-lapse microscopy in RPMI-1640 without phenol red in a 40/1.2 NA oil immersion objective Nikon Eclipse Ti microscope with an ORCA-Flash 4.0 camera (Hamamatsu) and Metamorph software (Molecular Devices)

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Willems MET, Sahin MA, Cook MD

Net weight: 92 g

The therapeutic potential of targeting the SIRT1/Nrf2/HO-1/GPX4 pathway is further supported by research indicating that edaravone, a widely used anesthetic, mitigates depression and anxiety by inhibiting ferroptosis through this pathway (Shen et al., 1826)

Should not be used during pregnancy and for at least two months before a planned pregnancy because it is not known if it may affect your unborn child