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The data showed higher prevalence of anemia and cognitive impairment in those participants with vitamin B-12 deficiency [defined as serum vitamin B-12 concentration 1594 nmol/L) was associated with lower Mini-Mental State Examination (MMSE) scores than seen with low vitamin B-12 status in combination with nonelevated RBC folate (24)

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Centella is widely used because it is effective at low percentages