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[DOI] [PubMed] [Google Scholar] 140.Holick M.F
Should you take Wegovy or Zepbound
Youre allergic to semaglutide or any of its ingredients
Use of GLP-1RA is protective and prevents bone fractures over a longer period of use in T2DM patients in a recent trial in 2020 liraglutide showed to have decreased bone resorption compared to placebo (120)
After weight loss: Brain reward circuits become hyperactive in response to food cues Prefrontal cortex inhibitory control becomes less effective Dopamine signaling changes make food more rewarding These changes persist for years, possibly permanently Youre not imagining that food seems more appealing after weight loss
No cases of medullary thyroid cancer or related conditions were reported in trials, but medications in the GLP-1 class carry a warning based on animal studies, which is something to go over with your doctor if you have a related history
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