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Vitamin B12 Deficiency: Insufficient dietary intake of B12 (common in vegetarians and vegans), Malabsorption due to conditions like pernicious anemia or gastrointestinal disorders (e.g., Crohns disease), Certain medications that interfere with B12 absorption can lead to deficiency

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Am J Clin Dermatol 19(1):6777

Moreover, they influence gene expression related to fatty acid oxidation, reduce fat absorption, and promote the expression of proteins like Angiopoietin-like 4 (ANGPTL4), which inhibits enzymes responsible for fat storage